Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FrgASiderophore biosynthetic enzyme FrgA; Function of strongly homologous gene; enzyme. (578 aa)    
Predicted Functional Partners:
iucD
L-lysine 6-monooxygenase (NADPH); Function of strongly homologous gene; enzyme.
 
  
 0.919
LHA_2609
Putative Aspartate racemase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
  
 0.839
LHA_3008
Drug resistance transporter, Bcr/CflA.
 
   
 0.831
LHA_3007
Multidrug resistance efflux pump.
  
  
 0.791
LHA_3010
Homologs of previously reported genes of unknown function; Belongs to the DnaA family. HdA subfamily.
       0.777
LHA_3009
Phosphatidylglycerophosphate synthase (modular protein); Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
       0.774
LHA_3005
Exported protein of unknown function; No homology to any previously reported sequences.
       0.543
LHA_0403
Putative integral membrane protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
     0.531
LHA_2765
Membrane protein of unknown function; No homology to any previously reported sequences.
  
     0.518
LHA_1354
Putative coiled-coil protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
     0.510
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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