Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
LHA_3014Homologs of previously reported genes of unknown function. (191 aa)    
Predicted Functional Partners:
dtpB
Dipeptide and tripeptide permease B.
       0.807
LHA_2338
Endo-1,3(4)-beta-glucanase; Function of strongly homologous gene; enzyme.
  
     0.714
LHA_0385
Protein of unknown function [ankyrin repeat]; No homology to any previously reported sequences.
  
 
  0.658
LHA_2947
Serine/threonine-protein kinase; Function of strongly homologous gene; enzyme.
  
     0.623
LHA_3016
Membrane protein of unknown function; No homology to any previously reported sequences.
       0.586
epd
D-erythrose 4-phosphate dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
 
 0.562
LHA_3158
PAS sensor histidine kinase domain protein.
 
     0.553
cdd
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
    
 0.547
LHA_1362
Homologs of previously reported genes of unknown function.
  
     0.498
LHA_2586
Putative Transcription regulator LuxR, C-terminal; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
  
     0.488
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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