Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LHA_3120Putative methyltransferases; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (234 aa)    
Predicted Functional Partners:
LHA_3119
Homologs of previously reported genes of unknown function.
       0.866
LHA_3118
Homologs of previously reported genes of unknown function.
       0.741
LHA_0648
Transporter, Zip family.
 
     0.715
icmE/dotG
Component of the Dot/Icm secretion system. Major component of a channel; Function of strongly homologous gene; structure.
  
     0.663
dotA
Component of the Dot/Icm secretion system; Function of strongly homologous gene; membrane component.
  
    0.652
LHA_3117
Protein of unknown function; No homology to any previously reported sequences.
       0.649
LHA_3048
Tubulin--tyrosine ligase [TTL domain]; Function of strongly homologous gene; enzyme.
  
     0.605
LHA_2859
Homolog of LvrA protein.
  
     0.595
LHA_2930
Homologs of previously reported genes of unknown function.
 
     0.591
LHA_3178
Cysteine protease, papain C1 family.
  
     0.564
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
Server load: medium (46%) [HD]