Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LHA_3127Homologs of previously reported genes of unknown function. (542 aa)    
Predicted Functional Partners:
LHA_0403
Putative integral membrane protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
     0.753
LHA_0593
Conserved protein of unknown function [ankyrin repeat]; Homologs of previously reported genes of unknown function.
  
    0.719
nfeD
Membrane bound peptidase; Function of strongly homologous gene; enzyme.
       0.716
LHA_0183
Homologs of previously reported genes of unknown function.
 
     0.714
LHA_1354
Putative coiled-coil protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
     0.696
icmB
IcmB protein.
  
    0.693
LHA_2765
Membrane protein of unknown function; No homology to any previously reported sequences.
  
     0.689
iraA
Small-molecule methyltransferase IraA; Function of strongly homologous gene; enzyme.
  
     0.681
LHA_1417
Putative Enhanced entry protein EnhA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; cell process.
  
     0.678
LHA_2281
Exported protein of unknown function; No homology to any previously reported sequences.
  
     0.663
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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