Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LHA_3131Putative Sodium-type flagellar protein motY precursor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; structure. (294 aa)    
Predicted Functional Partners:
tolB
Protein tolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
 
 
 0.809
IcmN/DotK
Component of the Dot/Icm secretion system. Lipoprotein of the OmpA protein family; Function of strongly homologous gene; lipoprotein.
  
 
   0.805
lolA
Outer-membrane lipoprotein carrier protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
  
 
 0.644
icmE/dotG
Component of the Dot/Icm secretion system. Major component of a channel; Function of strongly homologous gene; structure.
  
 
 0.640
LHA_2926
Conserved exported protein of unknown function; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
   
 
 0.634
pyrC
Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
  
    0.632
rnt
Ribonuclease T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.
       0.632
LHA_0609
Outer membrane protein OmpH; Belongs to the skp family.
  
 
 0.624
flgC
Flagellar basal-body rod protein flgC.
   
   0.624
lolC
Lipoprotein-releasing system transmembrane protein lolC.
  
 
 
 0.583
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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