STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ydhDMonothiol glutaredoxin; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the glutaredoxin family. Monothiol subfamily. (105 aa)    
Predicted Functional Partners:
bolA
Protein BolA; Belongs to the BolA/IbaG family.
 
 
 0.906
LHA_3134
Putative peroxiredoxin; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
 
 0.844
sodB
Superoxide dismutase [Fe]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
  
 0.794
LHA_2096
Homologs of previously reported genes of unknown function; Belongs to the BolA/IbaG family.
 
 
 
 0.694
argD
Acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
       0.657
trxA-2
Thioredoxin; Belongs to the thioredoxin family.
   
  
 0.604
msrA
Bifunctional methionine sulfoxide reductase B/A protein; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
      
 0.589
iscA
Iron-binding protein iscA; Belongs to the HesB/IscA family.
 
 0.577
yadR
Putative chaperone involved in Fe-S cluster assembly and activation; Required for insertion of 4Fe-4S clusters for at least IspG.
  
 0.565
ubiH
2-octaprenyl-6-methoxyphenol hydroxylase.
  
    0.564
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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