STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LHA_3194Putative helicase/relaxase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (447 aa)    
Predicted Functional Partners:
tolR
Protein tolR; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
  
 
 0.988
tolQ
Protein tolQ; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
  
 
 0.961
LHA_2334
Exported protein of unknown function; No homology to any previously reported sequences.
  
 
 0.898
LHA_3189
Homologs of previously reported genes of unknown function.
 
     0.803
apaH
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family.
       0.803
LHA_3191
ABC transporter, permease protein.
  
    0.792
lolD-3
Lipoprotein-releasing system ATP-binding protein LolD 1.
  
  
 0.788
LHA_3192
Homologs of previously reported genes of unknown function; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
  
 0.787
LHA_0593
Conserved protein of unknown function [ankyrin repeat]; Homologs of previously reported genes of unknown function.
  
 
   0.769
dotA
Component of the Dot/Icm secretion system; Function of strongly homologous gene; membrane component.
  
     0.767
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.