STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LHA_3245Homologs of previously reported genes of unknown function; Belongs to the UPF0102 family. (119 aa)    
Predicted Functional Partners:
gmhA
Phosphoheptose isomerase.
  
    0.881
LHA_3243
Periplasmic protein.
       0.855
LHA_3242
Puttaive lipoproteins.
       0.838
LHA_3246
Homologs of previously reported genes of unknown function.
  
  
 0.797
LHA_0827
Homologs of previously reported genes of unknown function.
 
    0.733
yraL
Putative methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
       0.689
comM
Competence protein ComM.
 
  
 0.678
smf
Protein smf (DNA-processing chain A); Function of strongly homologous gene; cell process.
 
  
 0.587
topA
DNA topoisomerase; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superc [...]
       0.461
LHA_2445
Diguanylate cyclase; No homology to any previously reported sequences;/product='fragment of protein of unknown function'.
  
    0.419
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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