STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHL42160.14a-hydroxytetrahydrobiopterin dehydratase. (112 aa)    
Predicted Functional Partners:
SHL42193.1
Phenylalanine 4-hydroxylase.
 
 0.998
SHL42136.1
Aromatic-amino-acid transaminase.
  
  
 0.949
SHL42425.1
4-hydroxyphenylpyruvate dioxygenase.
  
  
 0.792
hmgA
Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
  
  
 0.686
moaC
Cyclic pyranopterin phosphate synthase; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.
   
  
 0.502
SHL64992.1
Protein of unknown function.
  
  
 0.500
purL
Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
      
 0.431
SHM93132.1
Chorismate mutase.
      
 0.428
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
   
  
 0.400
Your Current Organism:
Halomonas cupida
NCBI taxonomy Id: 44933
Other names: ATCC 27124, Alcaligenes cupidus, CCUG 16075, CIP 103199, DSM 4740, Deleya cupida, H. cupida, JCM 20632, LMG 3448, LMG:3448, NBRC 102219, strain 79
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