node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SHL47040.1 | SHL47107.1 | SAMN05660971_00668 | SAMN05660971_00670 | ATP-dependent helicase HrpB. | SEC-C motif-containing protein. | 0.531 |
SHL47040.1 | glsA | SAMN05660971_00668 | SAMN05660971_00669 | ATP-dependent helicase HrpB. | L-glutaminase; Belongs to the glutaminase family. | 0.487 |
SHL47107.1 | SHL47040.1 | SAMN05660971_00670 | SAMN05660971_00668 | SEC-C motif-containing protein. | ATP-dependent helicase HrpB. | 0.531 |
SHL47107.1 | SHL47141.1 | SAMN05660971_00670 | SAMN05660971_00671 | SEC-C motif-containing protein. | Protein of unknown function. | 0.730 |
SHL47107.1 | SHM94856.1 | SAMN05660971_00670 | SAMN05660971_04353 | SEC-C motif-containing protein. | Putative endonuclease. | 0.502 |
SHL47107.1 | ffh | SAMN05660971_00670 | SAMN05660971_01653 | SEC-C motif-containing protein. | Signal recognition particle subunit FFH/SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the i [...] | 0.467 |
SHL47107.1 | glsA | SAMN05660971_00670 | SAMN05660971_00669 | SEC-C motif-containing protein. | L-glutaminase; Belongs to the glutaminase family. | 0.509 |
SHL47107.1 | secY | SAMN05660971_00670 | SAMN05660971_03360 | SEC-C motif-containing protein. | Protein translocase subunit secY/sec61 alpha; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.549 |
SHL47107.1 | yidC | SAMN05660971_00670 | SAMN05660971_02354 | SEC-C motif-containing protein. | Protein translocase subunit yidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.524 |
SHL47141.1 | SHL47107.1 | SAMN05660971_00671 | SAMN05660971_00670 | Protein of unknown function. | SEC-C motif-containing protein. | 0.730 |
SHL47141.1 | glsA | SAMN05660971_00671 | SAMN05660971_00669 | Protein of unknown function. | L-glutaminase; Belongs to the glutaminase family. | 0.468 |
SHM94856.1 | SHL47107.1 | SAMN05660971_04353 | SAMN05660971_00670 | Putative endonuclease. | SEC-C motif-containing protein. | 0.502 |
ffh | SHL47107.1 | SAMN05660971_01653 | SAMN05660971_00670 | Signal recognition particle subunit FFH/SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the i [...] | SEC-C motif-containing protein. | 0.467 |
ffh | secY | SAMN05660971_01653 | SAMN05660971_03360 | Signal recognition particle subunit FFH/SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the i [...] | Protein translocase subunit secY/sec61 alpha; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.990 |
ffh | yidC | SAMN05660971_01653 | SAMN05660971_02354 | Signal recognition particle subunit FFH/SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the i [...] | Protein translocase subunit yidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.955 |
glsA | SHL47040.1 | SAMN05660971_00669 | SAMN05660971_00668 | L-glutaminase; Belongs to the glutaminase family. | ATP-dependent helicase HrpB. | 0.487 |
glsA | SHL47107.1 | SAMN05660971_00669 | SAMN05660971_00670 | L-glutaminase; Belongs to the glutaminase family. | SEC-C motif-containing protein. | 0.509 |
glsA | SHL47141.1 | SAMN05660971_00669 | SAMN05660971_00671 | L-glutaminase; Belongs to the glutaminase family. | Protein of unknown function. | 0.468 |
secY | SHL47107.1 | SAMN05660971_03360 | SAMN05660971_00670 | Protein translocase subunit secY/sec61 alpha; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | SEC-C motif-containing protein. | 0.549 |
secY | ffh | SAMN05660971_03360 | SAMN05660971_01653 | Protein translocase subunit secY/sec61 alpha; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | Signal recognition particle subunit FFH/SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the i [...] | 0.990 |