STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHM34849.1MerR HTH family regulatory protein. (163 aa)    
Predicted Functional Partners:
SHM34825.1
Protein of unknown function.
 
     0.810
SHM09872.1
Diguanylate cyclase (GGDEF) domain-containing protein.
    
 0.742
SHL86415.1
Two-component system, NarL family, sensor histidine kinase EvgS.
    
 0.613
rpoD
RNA polymerase, sigma 70 subunit, RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
   
   0.607
dnaJ
Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]
  
 
 0.605
SHL99241.1
PAS domain S-box-containing protein/diguanylate cyclase (GGDEF) domain-containing protein.
    
 0.595
SHL30011.1
Protein of unknown function.
 
     0.574
SHL40240.1
PAS domain S-box-containing protein/diguanylate cyclase (GGDEF) domain-containing protein.
    
  0.562
SHM11310.1
Diguanylate cyclase (GGDEF) domain-containing protein.
    
  0.562
SHM24672.1
PAS domain S-box-containing protein/diguanylate cyclase (GGDEF) domain-containing protein.
    
  0.562
Your Current Organism:
Halomonas cupida
NCBI taxonomy Id: 44933
Other names: ATCC 27124, Alcaligenes cupidus, CCUG 16075, CIP 103199, DSM 4740, Deleya cupida, H. cupida, JCM 20632, LMG 3448, LMG:3448, NBRC 102219, strain 79
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