STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pgi-3Glucose-6-phosphate isomerase; Belongs to the GPI family. (547 aa)    
Predicted Functional Partners:
pfp
Pyrophosphate-dependent phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
  
 0.974
SHM80201.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
 
 
 0.966
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
  
 0.955
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
 0.949
SHM44338.1
Phosphoglucomutase.
 
 0.947
SHM89206.1
Phosphocarrier protein HPr/phosphoenolpyruvate--protein phosphotransferase.
  
 
 0.936
SHM67852.1
Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
  
 
 0.932
SHM70066.1
Glyceraldehyde-3-phosphate dehydrogenase (NAD+); Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
 
 0.925
glk
Glucokinase; Belongs to the bacterial glucokinase family.
 
  
 0.917
pgk
Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
 
 0.904
Your Current Organism:
Halomonas cupida
NCBI taxonomy Id: 44933
Other names: ATCC 27124, Alcaligenes cupidus, CCUG 16075, CIP 103199, DSM 4740, Deleya cupida, H. cupida, JCM 20632, LMG 3448, LMG:3448, NBRC 102219, strain 79
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