Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
C2G38_2230604Thymidylate synthase. (299 aa)    
Predicted Functional Partners:
C2G38_1770584
Dihydrofolate reductase-like domain-containing protein; Belongs to the dihydrofolate reductase family.
 
 
 0.978
C2G38_1992046
Queuine tRNA-ribosyltransferase catalytic subunit 1; Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, formi [...]
 
 
    0.905
C2G38_1989341
Phosphoribosylglycinamide formyltransferase.
   
 
 0.848
C2G38_1978006
Uncharacterized protein.
  
 
 0.848
C2G38_2318760
Phosphoribosylglycinamide synthetase.
   
 
 0.846
C2G38_1569287
Flavo protein.
 
   
 0.831
C2G38_2013229
Rhodanese domain-containing protein.
     
 0.829
C2G38_2199381
Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine.
    
 0.823
C2G38_2250045
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
  
 
 0.820
C2G38_2017168
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
  
 
 0.820
Your Current Organism:
Gigaspora rosea
NCBI taxonomy Id: 44941
Other names: G. rosea
Server load: medium (50%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.