Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
C2G38_2049808RING-type domain-containing protein. (426 aa)    
Predicted Functional Partners:
C2G38_2003874
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.902
C2G38_2133301
Ubiquitin-conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.877
C2G38_62160
Uncharacterized protein.
    
 0.868
C2G38_2133103
FACT complex subunit-domain-containing protein.
    
 
 0.863
C2G38_1962530
FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...]
    
 
 0.860
C2G38_2074506
Kinase-like domain-containing protein.
    
 0.859
C2G38_2008081
Histone-fold-containing protein.
    
 0.837
C2G38_1974740
Histone H3; Belongs to the histone H3 family.
    
 0.837
C2G38_2037077
Histone H3; Belongs to the histone H3 family.
    
 0.837
C2G38_2035361
Histone H2B; Belongs to the histone H2B family.
    
  0.835
Your Current Organism:
Gigaspora rosea
NCBI taxonomy Id: 44941
Other names: G. rosea
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