Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
C2G38_1983427Dynein heavy chain. (4645 aa)    
Predicted Functional Partners:
C2G38_2131876
Dynein light chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures.
    
 0.900
C2G38_1967350
Tctex-1.
    
 0.899
C2G38_2007486
Dynein light chain roadblock.
    
 0.893
C2G38_2211939
Dynein light intermediate chain-domain-containing protein.
    
 0.893
PAC1
Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs; Belongs to the WD repeat LIS1/nudF family.
    
 0.892
C2G38_1986575
Calponin homology domain-containing protein.
    
 0.851
C2G38_2133487
Phosphatase 1 regulatory subunit SDS22.
    
 0.837
C2G38_2208332
Uncharacterized protein.
    
 0.815
C2G38_2074506
Kinase-like domain-containing protein.
    
 0.811
C2G38_1974219
Urease; In the C-terminal section; belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
    
 0.808
Your Current Organism:
Gigaspora rosea
NCBI taxonomy Id: 44941
Other names: G. rosea
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