Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MAE_03210Two-component sensor histidine kinase. (483 aa)    
Predicted Functional Partners:
MAE_31720
Two-component hybrid sensor and regulator.
 
 
 0.796
MAE_37480
Two-component hybrid sensor and regulator.
 
 
 
 0.736
MAE_21690
Two-component hybrid histidine kinase.
 
 
 
 0.730
sasA
Clock-associated histidine kinase; May be involved in signal transduction. Participates in the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with KaiC. Required for robustness of the circadian rhythm of gene expression and is involved in clock outputs.
  
 
 
 0.677
MAE_36080
Two-component sensor histidine kinase.
  
 
 
 0.662
MAE_14410
Two-component sensor histidine kinase.
  
 
 
 0.630
MAE_48940
Two-component sensor histidine kinase.
  
   
 0.616
MAE_02100
Two-component sensor histidine kinase.
  
 
 
 0.590
MAE_52650
Two-component sensor histidine kinase.
  
 
 
 0.583
MAE_41270
Two-component hybrid sensor and regulator.
 
 
 0.555
Your Current Organism:
Microcystis aeruginosa
NCBI taxonomy Id: 449447
Other names: M. aeruginosa NIES-843, Microcystis aeruginosa NIES-843
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.