STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAE_12270Cyanobacterial phytochrome; Two-component sensor histidine kinase. (768 aa)    
Predicted Functional Partners:
MAE_12260
Two-component response regulator; CheY subfamily.
 
 0.998
MAE_21690
Two-component hybrid histidine kinase.
 
 
 
0.880
kaiA
Circadian clock protein KaiA homolog; Component of the kaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The kaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it enhances the phosphorylation status of kaiC. In contrast, the presence of kaiB in the complex decreases the phosphorylation status of kaiC, suggesting that kaiB acts by antagonizing the interaction between kaiA and kaiC. A kaiA dimer is sufficient to enhance [...]
   
 
 0.739
MAE_44610
Two-component hybrid sensor and regulator.
 
 
0.687
MAE_12250
Two-component hybrid histidine kinase.
 
   
0.684
kaiC
Circadian clock protein KaiC homolog; Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction; Belongs to the KaiC family.
 
 
 
 0.678
kaiC-2
Circadian clock protein KaiC homolog.
 
 
 
 0.671
MAE_22800
Serine/threonine kinase.
   
 0.609
MAE_37480
Two-component hybrid sensor and regulator.
 
 
 
0.586
MAE_24870
Peptidase C14, caspase catalytic subunit P20.
      
 0.571
Your Current Organism:
Microcystis aeruginosa
NCBI taxonomy Id: 449447
Other names: M. aeruginosa NIES-843, Microcystis aeruginosa NIES-843
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.