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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRN98583.1Dihydrolipoamide dehydrogenase. (468 aa)    
Predicted Functional Partners:
KRN98582.1
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
 0.998
KRN98546.1
Branched-chain alpha-keto acid dehydrogenase subunit E2.
 0.996
KRN98581.1
Pyruvate dehydrogenase E1 component beta subunit.
 0.992
pdhA
Pyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
 
 0.980
KRN98547.1
Pyruvate dehydrogenase complex E1 component beta subunit.
 
 0.951
KRN96498.1
Thioredoxin.
  
 0.858
KRN98584.1
Lipoate-protein ligase A.
 
 
 0.850
KRO01139.1
Lipoate-protein ligase.
 
 
 0.834
KRN95844.1
Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.789
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.765
Your Current Organism:
Lactobacillus pobuzihii
NCBI taxonomy Id: 449659
Other names: JCM 18084, KCTC 13174, L. pobuzihii, Lactobacillus pobuzihii Chen et al. 2010, NBRC 103219, RIFY 6501, strain E100301
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