Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Lade_0697Lipopolysaccharide biosynthesis protein. (428 aa)    
Predicted Functional Partners:
rfbD
dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family.
 
  
 0.859
Lade_0693
Glycosyltransferase, group 1 family.
  
  
 0.854
mfpsA
Glycosyltransferase.
  
    0.851
wecB
UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
  
  
 0.850
hyaD
Glycosyl transferase, family 2.
 
    0.832
capD_1
NAD dependent epimerase/dehydratase.
  
  
 0.813
galE
UDP-glucose 4-epimerase.
  
    0.776
rmd
GDP-6-deoxy-D-mannose reductase.
  
    0.749
ugd
UDP-glucose 6-dehydrogenase.
  
  
 0.736
pagP
Antimicrobial peptide resistance and lipid A acylation PagP; Transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors.
  
     0.578
Your Current Organism:
Legionella adelaidensis
NCBI taxonomy Id: 45056
Other names: ATCC 49625, CCUG 31231 A, CIP 103645, DSM 19888, L. adelaidensis, NCTC 12735
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