STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lade_2007AraC family transcriptional regulator. (242 aa)    
Predicted Functional Partners:
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.802
Lade_2008
Transmembrane protein.
     
 0.671
rpoD
RNA polymerase sigma 70 factor (RpoD); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
  
 
 
 0.593
adrA
Regulatory protein (GGDEF, PAS, PAC domains).
   
  
 0.516
arcB_4
Sensory histidine-kinase / response regulator.
   
  
 0.514
arcB_1
Sensory box histidine kinase/response regulator.
   
  
 0.514
Lade_1576
Sensory histidine-kinase / response regulator.
   
  
 0.514
arcB_3
Sensory box histidine kinase/response regulator.
   
  
 0.514
dhbF
Peptide synthetase, non-ribosomal; Belongs to the ATP-dependent AMP-binding enzyme family.
     
 0.513
pksJ
Polyketide synthase module.
      
 0.510
Your Current Organism:
Legionella adelaidensis
NCBI taxonomy Id: 45056
Other names: ATCC 49625, CCUG 31231 A, CIP 103645, DSM 19888, L. adelaidensis, NCTC 12735
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