STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lade_2008Transmembrane protein. (285 aa)    
Predicted Functional Partners:
dotG_1
IcmE/DotG protein.
 
 
   0.877
Lade_2007
AraC family transcriptional regulator.
     
 0.671
Lade_2067
Cysteine protease.
  
     0.572
Lade_1193
IcmK protein.
  
 
   0.506
secY
Preprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
   
   0.460
Lade_1165
Zip family transporter.
  
   0.449
Lade_2009
Hypothetical protein.
       0.448
Lade_2180
Protein-tyrosine phosphatase.
  
     0.428
Lade_1191
Protein IcmG (DotF).
    
   0.423
icmX
Intracellular multiplication protein IcmX.
    
   0.423
Your Current Organism:
Legionella adelaidensis
NCBI taxonomy Id: 45056
Other names: ATCC 49625, CCUG 31231 A, CIP 103645, DSM 19888, L. adelaidensis, NCTC 12735
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.