Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
Lade_2164Hypothetical protein; Alpha-2-macroglobulin family N-terminal region. (1924 aa)    
Predicted Functional Partners:
pbpC
Penicillin binding protein 1C.
   
 0.978
coq7
Ubiquinone biosynthesis protein; Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
       0.762
iraA
Small-molecule methyltransferase IraA.
  
     0.548
Lade_0397
LphB.
  
     0.521
nrdR
Transcriptional repressor of nrd; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.
    
   0.521
Lade_1074
Hypothetical protein.
  
     0.499
Lade_0264
Ankyrin repeats (3 copies).
  
     0.478
Lade_1185
IcmF.
  
    0.472
tolC_2
Outer membrane efflux protein.
  
     0.465
Lade_0752
Hypothetical protein.
  
     0.452
Your Current Organism:
Legionella adelaidensis
NCBI taxonomy Id: 45056
Other names: ATCC 49625, CCUG 31231 A, CIP 103645, DSM 19888, L. adelaidensis, NCTC 12735
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