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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
folK2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. (147 aa)    
Predicted Functional Partners:
folP
Dihydropteroate synthase.
 
 
 0.999
folB
Dihydroneopterin aldolase FolB.
  
 
 0.991
folE
GTP cyclohydrolase I.
 
  
 0.985
pcnB
poly(A) polymerase; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
  
    0.948
Lgee_0707
Putative molybdenum carrier.
  
  
 0.898
Lgee_0001
poly(A) polymerase I; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
  
    0.769
Lgee_0325
poly(A) polymerase I.
  
    0.765
folC
Dihydrofolate:folylpolyglutamate synthetase FolC; Belongs to the folylpolyglutamate synthase family.
 
  
 0.707
trpE
Anthranilate synthase.
  
  
 0.645
ribD
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
  
  
 0.617
Your Current Organism:
Legionella geestiana
NCBI taxonomy Id: 45065
Other names: ATCC 49504, CCUG 44893, CIP 105569, DSM 21217, L. geestiana, NCTC 12373
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