Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Lgee_0277Hypothetical protein. (996 aa)    
Predicted Functional Partners:
Lgee_0019
Putative transporter.
 
    0.836
rhsA
Putative deoxyribonuclease RhsA.
     
 0.624
Lgee_1732
Peptide synthetase, non-ribosomal.
    
 
 0.586
Lgee_0024
Sensory box histidine kinase/response regulator.
     
 0.559
Lgee_1507
Sensory box histidine kinase/response regulator.
     
 0.559
Lgee_0709
Regulatory protein (GGDEF and EAL domains).
     
 0.543
Lgee_0515
Preprotein translocase, secretion protein SecA.
 
   
 0.485
secA
Preprotein translocase, secretion protein SecA subunit.
 
   
 0.465
Lgee_0097
Serine/threonine-protein kinase.
  
     0.457
Lgee_0278
Hypothetical protein.
       0.443
Your Current Organism:
Legionella geestiana
NCBI taxonomy Id: 45065
Other names: ATCC 49504, CCUG 44893, CIP 105569, DSM 21217, L. geestiana, NCTC 12373
Server load: medium (44%) [HD]