Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Lgee_0311Hypothetical protein; Belongs to the UPF0125 (RnfH) family. (94 aa)    
Predicted Functional Partners:
Lgee_0312
Oligoketide cyclase/lipid transporter protein.
  
  
 0.942
Lgee_0313
Carboxylesterase/phospholipase.
       0.800
ppa
Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
       0.737
hinT
Purine nucleoside phosphoramidase.
       0.513
folE
GTP cyclohydrolase I.
       0.513
prpA
Phage repressor.
  
     0.508
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.508
Lgee_0741
Putative prophage repressor CI-like protein.
  
     0.507
dapF
Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.
       0.504
Lgee_1613
Hypothetical protein.
       0.504
Your Current Organism:
Legionella geestiana
NCBI taxonomy Id: 45065
Other names: ATCC 49504, CCUG 44893, CIP 105569, DSM 21217, L. geestiana, NCTC 12373
Server load: medium (48%) [HD]