smf protein (Legionella geestiana) - STRING interaction network

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Score

smf

Protein smf. (357 aa)

Predicted Functional Partners:

comF

0.978

comM

0.936

topA_1

0.930

comA

0.924

smg

0.863

Lgee_2061

0.858

recA

0.853

rsmB

0.809

def_1

0.772

fmt

0.761

Your Current Organism:

Legionella geestiana

NCBI taxonomy Id: 45065
Other names: ATCC 49504, CCUG 44893, CIP 105569, DSM 21217, L. geestiana, NCTC 12373

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Lgee_2061	comA	Lgee_2061	Lgee_0747	Type 4 (IV) prepilin-like protein leader peptide processing enzyme PilD; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.	DNA uptake/competence protein ComA.	0.918
Lgee_2061	smf	Lgee_2061	Lgee_0447	Type 4 (IV) prepilin-like protein leader peptide processing enzyme PilD; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.	Protein smf.	0.858
comA	Lgee_2061	Lgee_0747	Lgee_2061	DNA uptake/competence protein ComA.	Type 4 (IV) prepilin-like protein leader peptide processing enzyme PilD; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.	0.918
comA	comF	Lgee_0747	Lgee_1376	DNA uptake/competence protein ComA.	Competence protein ComF.	0.952
comA	comM	Lgee_0747	Lgee_1269	DNA uptake/competence protein ComA.	Competence related protein ComM.	0.609
comA	recA	Lgee_0747	Lgee_2276	DNA uptake/competence protein ComA.	Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.	0.706
comA	smf	Lgee_0747	Lgee_0447	DNA uptake/competence protein ComA.	Protein smf.	0.924
comF	comA	Lgee_1376	Lgee_0747	Competence protein ComF.	DNA uptake/competence protein ComA.	0.952
comF	comM	Lgee_1376	Lgee_1269	Competence protein ComF.	Competence related protein ComM.	0.951
comF	recA	Lgee_1376	Lgee_2276	Competence protein ComF.	Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.	0.791
comF	smf	Lgee_1376	Lgee_0447	Competence protein ComF.	Protein smf.	0.978
comM	comA	Lgee_1269	Lgee_0747	Competence related protein ComM.	DNA uptake/competence protein ComA.	0.609
comM	comF	Lgee_1269	Lgee_1376	Competence related protein ComM.	Competence protein ComF.	0.951
comM	recA	Lgee_1269	Lgee_2276	Competence related protein ComM.	Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.	0.737
comM	smf	Lgee_1269	Lgee_0447	Competence related protein ComM.	Protein smf.	0.936
def_1	fmt	Lgee_0448	Lgee_0449	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	Methionyl tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.	0.982
def_1	rsmB	Lgee_0448	Lgee_0450	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.	0.879
def_1	smf	Lgee_0448	Lgee_0447	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	Protein smf.	0.772
def_1	smg	Lgee_0448	Lgee_0446	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	Protein Smg.	0.761
def_1	topA_1	Lgee_0448	Lgee_0445	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]	0.721