| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| birA | rsmE_2 | Lgee_0909 | Lgee_0535 | biotin-[acetylCoA carboxylase] holoenzyme synthetase and biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 16S rRNA methyltransferase. | 0.471 |
| gidB | prmA | Lgee_1945 | Lgee_1665 | Glucose inhibited division protein B GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | Ribosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family. | 0.443 |
| gidB | rsmE_2 | Lgee_1945 | Lgee_0535 | Glucose inhibited division protein B GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | 16S rRNA methyltransferase. | 0.491 |
| gidB | rsmI | Lgee_1945 | Lgee_1853 | Glucose inhibited division protein B GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | Tetrapyrrole (corrin/porphyrin) methylase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 0.559 |
| prmA | gidB | Lgee_1665 | Lgee_1945 | Ribosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family. | Glucose inhibited division protein B GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | 0.443 |
| prmA | rsmE_2 | Lgee_1665 | Lgee_0535 | Ribosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family. | 16S rRNA methyltransferase. | 0.756 |
| rho | rsmE_2 | Lgee_0537 | Lgee_0535 | Hypothetical protein; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. | 16S rRNA methyltransferase. | 0.439 |
| rho | rsmI | Lgee_0537 | Lgee_1853 | Hypothetical protein; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. | Tetrapyrrole (corrin/porphyrin) methylase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 0.403 |
| rho | trxA | Lgee_0537 | Lgee_0536 | Hypothetical protein; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. | Thioredoxin; Belongs to the thioredoxin family. | 0.662 |
| rsmE_2 | birA | Lgee_0535 | Lgee_0909 | 16S rRNA methyltransferase. | biotin-[acetylCoA carboxylase] holoenzyme synthetase and biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.471 |
| rsmE_2 | gidB | Lgee_0535 | Lgee_1945 | 16S rRNA methyltransferase. | Glucose inhibited division protein B GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | 0.491 |
| rsmE_2 | prmA | Lgee_0535 | Lgee_1665 | 16S rRNA methyltransferase. | Ribosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family. | 0.756 |
| rsmE_2 | rho | Lgee_0535 | Lgee_0537 | 16S rRNA methyltransferase. | Hypothetical protein; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. | 0.439 |
| rsmE_2 | rsmI | Lgee_0535 | Lgee_1853 | 16S rRNA methyltransferase. | Tetrapyrrole (corrin/porphyrin) methylase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 0.425 |
| rsmE_2 | trxA | Lgee_0535 | Lgee_0536 | 16S rRNA methyltransferase. | Thioredoxin; Belongs to the thioredoxin family. | 0.694 |
| rsmI | gidB | Lgee_1853 | Lgee_1945 | Tetrapyrrole (corrin/porphyrin) methylase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | Glucose inhibited division protein B GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | 0.559 |
| rsmI | rho | Lgee_1853 | Lgee_0537 | Tetrapyrrole (corrin/porphyrin) methylase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | Hypothetical protein; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. | 0.403 |
| rsmI | rsmE_2 | Lgee_1853 | Lgee_0535 | Tetrapyrrole (corrin/porphyrin) methylase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 16S rRNA methyltransferase. | 0.425 |
| trxA | rho | Lgee_0536 | Lgee_0537 | Thioredoxin; Belongs to the thioredoxin family. | Hypothetical protein; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. | 0.662 |
| trxA | rsmE_2 | Lgee_0536 | Lgee_0535 | Thioredoxin; Belongs to the thioredoxin family. | 16S rRNA methyltransferase. | 0.694 |