Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
capLProtein capL; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (424 aa)    
Predicted Functional Partners:
wecB
UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
 
 
 0.991
glmU_1
Bifunctional protein GlmU.
  
 
 0.912
glmU_2
Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.
  
 
 0.912
Lgee_0615
NAD dependent epimerase/dehydratase family protein.
 
  
 0.867
Lgee_0120
Glycosyltransferase, group 1 family.
 
  
 0.784
Lgee_1603
Glycosyltransferase, group 1 family.
  
  
 0.741
Lgee_2084
Polysaccharide biosynthesis protein; Belongs to the DegT/DnrJ/EryC1 family.
 
  
 0.635
Lgee_0118
Aminotransferase WecE; Belongs to the DegT/DnrJ/EryC1 family.
 
  
 0.628
kanE
Alpha-D-kanosaminyltransferase.
 
  
 0.575
Lgee_0122
LPS O-antigen length regulator.
  
  
 0.531
Your Current Organism:
Legionella geestiana
NCBI taxonomy Id: 45065
Other names: ATCC 49504, CCUG 44893, CIP 105569, DSM 21217, L. geestiana, NCTC 12373
Server load: medium (48%) [HD]