Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Gene Fusion
Co-occurrence
Co-expression
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[Homology]
Score
hppD4-hydroxyphenylpyruvate dioxygenase. (352 aa)    
Predicted Functional Partners:
hmgA
Homogentisate 1,2-dioxygenase.
 
 0.998
maiA
Glutathione S-transferase (maleylacetoacetate isomerase).
 
  
 0.984
Lgee_0623
Fumarylacetoacetate hydrolase.
 
  
 0.979
phhA
Phenylalanine-4-hydroxylase.
 
  
 0.943
hisC-2
Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
    
 0.932
Lgee_0453
Phenylalanine-4-hydroxylase.
 
  
 0.929
aatA_1
Aspartate aminotransferase A.
   
 
 0.907
Lgee_1872
Aspartate aminotransferase.
   
 
 0.907
phs
Pterin 4 alpha carbinolamine dehydratase.
  
  
 0.895
Lgee_0626
Leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
 
   
 0.880
Your Current Organism:
Legionella geestiana
NCBI taxonomy Id: 45065
Other names: ATCC 49504, CCUG 44893, CIP 105569, DSM 21217, L. geestiana, NCTC 12373
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