| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Lgee_0916 | Lgee_1599 | Lgee_0916 | Lgee_1599 | Chloramphenicol acetyltransferase. | L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.933 |
| Lgee_0916 | cysK | Lgee_0916 | Lgee_1896 | Chloramphenicol acetyltransferase. | Cystathionine beta synthase. | 0.997 |
| Lgee_0916 | cysS | Lgee_0916 | Lgee_0992 | Chloramphenicol acetyltransferase. | cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.975 |
| Lgee_0916 | glyA | Lgee_0916 | Lgee_1197 | Chloramphenicol acetyltransferase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.846 |
| Lgee_0916 | metC | Lgee_0916 | Lgee_1828 | Chloramphenicol acetyltransferase. | Cystathionine beta-lyase. | 0.918 |
| Lgee_0916 | nadA | Lgee_0916 | Lgee_1589 | Chloramphenicol acetyltransferase. | Quinolinate synthetase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. | 0.837 |
| Lgee_0916 | trpA | Lgee_0916 | Lgee_0994 | Chloramphenicol acetyltransferase. | Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.803 |
| Lgee_0916 | trpB | Lgee_0916 | Lgee_0995 | Chloramphenicol acetyltransferase. | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.803 |
| Lgee_0916 | wecB | Lgee_0916 | Lgee_0919 | Chloramphenicol acetyltransferase. | UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. | 0.869 |
| Lgee_0916 | wecC | Lgee_0916 | Lgee_0918 | Chloramphenicol acetyltransferase. | UDP-glucose/GDP-mannose dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. | 0.842 |
| Lgee_1599 | Lgee_0916 | Lgee_1599 | Lgee_0916 | L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Chloramphenicol acetyltransferase. | 0.933 |
| Lgee_1599 | glyA | Lgee_1599 | Lgee_1197 | L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.970 |
| Lgee_1599 | metC | Lgee_1599 | Lgee_1828 | L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Cystathionine beta-lyase. | 0.840 |
| Lgee_1599 | trpA | Lgee_1599 | Lgee_0994 | L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.914 |
| Lgee_1599 | trpB | Lgee_1599 | Lgee_0995 | L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.900 |
| cysK | Lgee_0916 | Lgee_1896 | Lgee_0916 | Cystathionine beta synthase. | Chloramphenicol acetyltransferase. | 0.997 |
| cysK | cysS | Lgee_1896 | Lgee_0992 | Cystathionine beta synthase. | cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.868 |
| cysK | glyA | Lgee_1896 | Lgee_1197 | Cystathionine beta synthase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.434 |
| cysK | metC | Lgee_1896 | Lgee_1828 | Cystathionine beta synthase. | Cystathionine beta-lyase. | 0.998 |
| cysS | Lgee_0916 | Lgee_0992 | Lgee_0916 | cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | Chloramphenicol acetyltransferase. | 0.975 |