hutU protein (Legionella geestiana) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

hutU

Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (558 aa)

Predicted Functional Partners:

hutI

0.999

hutH

0.999

dnaQ

0.805

rnhA

0.805

hutG

0.687

enhA_2

0.660

Lgee_0971

0.595

rsfS

0.513

rlmH

0.513

mrdA

0.443

Your Current Organism:

Legionella geestiana

NCBI taxonomy Id: 45065
Other names: ATCC 49504, CCUG 44893, CIP 105569, DSM 21217, L. geestiana, NCTC 12373

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Lgee_0971	dnaQ	Lgee_0971	Lgee_0968	POT family transporter protein proton/peptide symporter.	DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.	0.595
Lgee_0971	enhA_2	Lgee_0971	Lgee_0967	POT family transporter protein proton/peptide symporter.	Enhanced entry protein EnhA.	0.479
Lgee_0971	hutU	Lgee_0971	Lgee_0970	POT family transporter protein proton/peptide symporter.	Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.	0.595
Lgee_0971	mrdA	Lgee_0971	Lgee_0974	POT family transporter protein proton/peptide symporter.	Penicillin binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.	0.560
Lgee_0971	rlmH	Lgee_0971	Lgee_0973	POT family transporter protein proton/peptide symporter.	rRNA large subunit methyltransferase; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.	0.673
Lgee_0971	rnhA	Lgee_0971	Lgee_0969	POT family transporter protein proton/peptide symporter.	Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.595
Lgee_0971	rsfS	Lgee_0971	Lgee_0972	POT family transporter protein proton/peptide symporter.	Ribosomal silencing factor RsfS; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.	0.673
dnaQ	Lgee_0971	Lgee_0968	Lgee_0971	DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.	POT family transporter protein proton/peptide symporter.	0.595
dnaQ	enhA_2	Lgee_0968	Lgee_0967	DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.	Enhanced entry protein EnhA.	0.668
dnaQ	hutU	Lgee_0968	Lgee_0970	DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.	Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.	0.805
dnaQ	mrdA	Lgee_0968	Lgee_0974	DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.	Penicillin binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.	0.535
dnaQ	rlmH	Lgee_0968	Lgee_0973	DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.	rRNA large subunit methyltransferase; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.	0.513
dnaQ	rnhA	Lgee_0968	Lgee_0969	DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.	Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.982
dnaQ	rsfS	Lgee_0968	Lgee_0972	DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.	Ribosomal silencing factor RsfS; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.	0.527
enhA_2	Lgee_0971	Lgee_0967	Lgee_0971	Enhanced entry protein EnhA.	POT family transporter protein proton/peptide symporter.	0.479
enhA_2	dnaQ	Lgee_0967	Lgee_0968	Enhanced entry protein EnhA.	DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.	0.668
enhA_2	hutU	Lgee_0967	Lgee_0970	Enhanced entry protein EnhA.	Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.	0.660
enhA_2	rnhA	Lgee_0967	Lgee_0969	Enhanced entry protein EnhA.	Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.666
hutG	hutH	Lgee_1210	Lgee_2248	Formiminoglutamase; Catalyzes the conversion of N-formimidoyl-L-glutamate to L- glutamate and formamide; Belongs to the arginase family.	Histidine ammonia lyase.	0.927
hutG	hutI	Lgee_1210	Lgee_1208	Formiminoglutamase; Catalyzes the conversion of N-formimidoyl-L-glutamate to L- glutamate and formamide; Belongs to the arginase family.	Imidazolonepropionase.	0.987