Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
gene fusions
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[Homology]
Score
mrdAPenicillin binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. (617 aa)    
Predicted Functional Partners:
rodA
Rod shape-determining protein rodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
 
 0.999
ponA
Penicillin binding protein 1A.
  
 
0.966
ftsW
Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily.
 
 0.954
dacA
D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5); Belongs to the peptidase S11 family.
  
 
 0.952
ftsI
Peptidoglycan synthetase FtsI precursor; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
  
  
0.948
mreC
Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape.
 
 
 0.945
pbpC
Penicillin binding protein 1C, peptidoglycan biosynthesis.
  
  
 0.945
dacB
D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase.
     
 0.934
Lgee_1581
Rod shape determining protein MreB.
 
 
 
 0.913
ftsQ
Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
  
 
 0.896
Your Current Organism:
Legionella geestiana
NCBI taxonomy Id: 45065
Other names: ATCC 49504, CCUG 44893, CIP 105569, DSM 21217, L. geestiana, NCTC 12373
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