Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
lrpRDNA-binding response regulator. (222 aa)    
Predicted Functional Partners:
qseC
Two component sensor kinase.
 
 0.998
Lgee_0024
Sensory box histidine kinase/response regulator.
 
 
 0.980
Lgee_0831
Sensory box histidine kinase/response regulator.
 
 
 0.980
Lgee_1507
Sensory box histidine kinase/response regulator.
 
 
0.975
Lgee_1733
Sensory box histidine kinase/response regulator.
 
 
0.962
gacS/letS
Transmission sensor LetS.
 
 
 0.959
Lgee_0287
Hypothetical protein.
  
 
 0.927
Lgee_1003
Intracellular septation protein A; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family.
 
     0.879
Lgee_1773
Sensor histidine kinase CpxA.
 
 
 0.847
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.793
Your Current Organism:
Legionella geestiana
NCBI taxonomy Id: 45065
Other names: ATCC 49504, CCUG 44893, CIP 105569, DSM 21217, L. geestiana, NCTC 12373
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