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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lgee_1202Multidrug efflux transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. (1013 aa)    
Predicted Functional Partners:
acrA
Acriflavin resistance protein E; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 0.997
Lgee_1053
Efflux protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 0.986
Lgee_1217
Outer membrane protein TolC.
  
 0.962
lmxE
Efflux protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.917
Lgee_1054
Integral membrane protein, AcrB/AcrD/AcrF family; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
  
 
0.915
lprN
Outer membrane efflux protein.
 
 0.797
helB
HelB protein.
 
 
 0.747
yajC
SecYEG protein translocase auxillary subunit; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.
    
 
 0.640
valS
valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
       0.594
helC
HelC protein.
  
 
 0.581
Your Current Organism:
Legionella geestiana
NCBI taxonomy Id: 45065
Other names: ATCC 49504, CCUG 44893, CIP 105569, DSM 21217, L. geestiana, NCTC 12373
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