Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
trxBThioredoxin reductase. (318 aa)    
Predicted Functional Partners:
trxA
Thioredoxin; Belongs to the thioredoxin family.
 
 
 0.972
sufS
Selenocysteine lyase, PLP-dependent; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.
 
 
  0.918
ahpC
Alkyl hydroperoxide reductase.
  
 
 0.917
metC
Cystathionine beta-lyase.
   
 
 0.910
trxA3
Thioredoxin; Belongs to the thioredoxin family.
 
 
 0.904
Lgee_0824
Ferredoxin reductase.
   
 
 0.853
lolA
Outer membrane lipoprotein carrier protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
  
    0.818
ftsK
Cell division protein FtsK.
 
    0.806
ccmG
Cytochrome C biogenesis protein.
   
 
 0.791
resA
Thiol-disulfide oxidoreductase ResA.
   
 
 0.791
Your Current Organism:
Legionella geestiana
NCBI taxonomy Id: 45065
Other names: ATCC 49504, CCUG 44893, CIP 105569, DSM 21217, L. geestiana, NCTC 12373
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