Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
umuDSOS error prone mutagenesis protein UmuD (RumA); Belongs to the peptidase S24 family. (168 aa)    
Predicted Functional Partners:
umuC
DNA polymerase V, subunit C.
 
 
 0.997
recA
Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 
 0.991
recN
DNA repair protein recN; May be involved in recombinational repair of damaged DNA.
   
  
 0.913
Lgee_1411
SNF2/RAD54 family transporter domain-containing protein.
       0.661
recX
Recombination regulator RecX; Modulates RecA activity; Belongs to the RecX family.
   
  
 0.630
Lgee_1408
Rhodanese domain protein.
       0.596
mutH
DNA mismatch repair protein; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair. Belongs to the MutH family.
   
  
 0.533
uvrA
Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
  
  
 0.527
htpB
Molecular chaperone GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
      
 0.517
groES
Co-chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
      
 0.516
Your Current Organism:
Legionella geestiana
NCBI taxonomy Id: 45065
Other names: ATCC 49504, CCUG 44893, CIP 105569, DSM 21217, L. geestiana, NCTC 12373
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