Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
helAHelA protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. (1051 aa)    
Predicted Functional Partners:
helC
HelC protein.
 
  
 0.988
helB
HelB protein.
 
 
 0.987
lmxE
Efflux protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.798
Lgee_1053
Efflux protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.773
acrA
Acriflavin resistance protein E; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.707
lprN
Outer membrane efflux protein.
 
  
 0.667
Lgee_1498
Hypothetical protein.
       0.596
Lgee_1502
Methyltransferase domain protein.
       0.541
queF
GTP cyclohydrolase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
      
 0.539
czcD
Cation efflux system protein.
     
 0.479
Your Current Organism:
Legionella geestiana
NCBI taxonomy Id: 45065
Other names: ATCC 49504, CCUG 44893, CIP 105569, DSM 21217, L. geestiana, NCTC 12373
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