Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Lgee_1541Sigma 54-dependent response regulator. (433 aa)    
Predicted Functional Partners:
Lgee_1542
Sensor kinase HydH.
 
 0.995
rpoN
RNA polymerase sigma-54 factor (sigma-L); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
   
 0.917
Lgee_1362
Flagellar biosynthesis MinD.
  
 
 0.881
Lgee_1540
Transmembrane protein.
       0.836
Lgee_1036
Flagellar protein.
 
  
 0.823
fliE
Flagellar hook-basal body complex protein.
 
  
 0.789
mpl
UDP-N-acetylmuramate-L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase.
       0.767
flgD_1
Flagellar basal body rod modification protein; Required for flagellar hook formation. May act as a scaffolding protein.
  
  
 0.761
Lgee_0709
Regulatory protein (GGDEF and EAL domains).
  
 
 0.745
fliG
Flagellar motor switch protein.
  
  
 0.723
Your Current Organism:
Legionella geestiana
NCBI taxonomy Id: 45065
Other names: ATCC 49504, CCUG 44893, CIP 105569, DSM 21217, L. geestiana, NCTC 12373
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