| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Lgee_0552 | guaB | Lgee_0552 | Lgee_1059 | Inosine 5'-monophosphate dehydrogenase. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.920 |
| Lgee_0552 | metG | Lgee_0552 | Lgee_1954 | Inosine 5'-monophosphate dehydrogenase. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.511 |
| Lgee_0552 | pepP | Lgee_0552 | Lgee_1908 | Inosine 5'-monophosphate dehydrogenase. | Proline aminopeptidase P II. | 0.569 |
| Lgee_2000 | pepP | Lgee_2000 | Lgee_1908 | Oligopeptidase A. | Proline aminopeptidase P II. | 0.500 |
| efp | metG | Lgee_2008 | Lgee_1954 | Translation elongation factor P (EF-P); Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation; Belongs to the elongation factor P family. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.600 |
| efp | pepP | Lgee_2008 | Lgee_1908 | Translation elongation factor P (EF-P); Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation; Belongs to the elongation factor P family. | Proline aminopeptidase P II. | 0.568 |
| guaB | Lgee_0552 | Lgee_1059 | Lgee_0552 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Inosine 5'-monophosphate dehydrogenase. | 0.920 |
| guaB | metG | Lgee_1059 | Lgee_1954 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.511 |
| guaB | pepP | Lgee_1059 | Lgee_1908 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Proline aminopeptidase P II. | 0.569 |
| korA | pepP | Lgee_1158 | Lgee_1908 | 2-oxoglutarate ferredoxin oxidoreductase subunit alpha. | Proline aminopeptidase P II. | 0.525 |
| metG | Lgee_0552 | Lgee_1954 | Lgee_0552 | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | Inosine 5'-monophosphate dehydrogenase. | 0.511 |
| metG | efp | Lgee_1954 | Lgee_2008 | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | Translation elongation factor P (EF-P); Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation; Belongs to the elongation factor P family. | 0.600 |
| metG | guaB | Lgee_1954 | Lgee_1059 | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.511 |
| metG | pepP | Lgee_1954 | Lgee_1908 | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | Proline aminopeptidase P II. | 0.585 |
| nadE | pepP | Lgee_0841 | Lgee_1908 | Glutamine dependent NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | Proline aminopeptidase P II. | 0.498 |
| pepP | Lgee_0552 | Lgee_1908 | Lgee_0552 | Proline aminopeptidase P II. | Inosine 5'-monophosphate dehydrogenase. | 0.569 |
| pepP | Lgee_2000 | Lgee_1908 | Lgee_2000 | Proline aminopeptidase P II. | Oligopeptidase A. | 0.500 |
| pepP | efp | Lgee_1908 | Lgee_2008 | Proline aminopeptidase P II. | Translation elongation factor P (EF-P); Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation; Belongs to the elongation factor P family. | 0.568 |
| pepP | guaB | Lgee_1908 | Lgee_1059 | Proline aminopeptidase P II. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.569 |
| pepP | korA | Lgee_1908 | Lgee_1158 | Proline aminopeptidase P II. | 2-oxoglutarate ferredoxin oxidoreductase subunit alpha. | 0.525 |