Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
rimIGCN5-related N-acetyltransferase; Acetylates the N-terminal alanine of ribosomal protein S18. (155 aa)    
Predicted Functional Partners:
lpdA
Dihydrolipoamide dehydrogenase.
       0.715
aceF
Pyruvate dehydrogenase E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
       0.706
Lgee_2039
Inner membrane protein AmpE.
       0.671
kefC
Sodium/hydrogen antiporter.
       0.671
aceE
Pyruvate dehydrogenase E1 component oxidoreductase protein AceE; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
       0.621
TsaB
Glycoprotease.
  
 
 0.477
Lgee_2038
Acyltransferase.
       0.469
prfC
Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
  
  
 0.462
Lgee_0159
N-acetyltransferase; Multifunctional nucleotidyltransferase/glutamate rich protein GrpB/ribosomal protein alanine acetyltransferase.
  
 
 0.428
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.405
Your Current Organism:
Legionella geestiana
NCBI taxonomy Id: 45065
Other names: ATCC 49504, CCUG 44893, CIP 105569, DSM 21217, L. geestiana, NCTC 12373
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