Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Lgee_2052Hypothetical protein; Alpha-2-macroglobulin family N-terminal region. (1904 aa)    
Predicted Functional Partners:
pbpC
Penicillin binding protein 1C, peptidoglycan biosynthesis.
   
 0.984
nrdR
NrdR family transcriptional regulator; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.
    
   0.679
Lgee_2280
IcmF.
  
    0.565
Lgee_1611
Hypothetical protein.
  
     0.523
Lgee_1631
LphB.
  
     0.468
Lgee_1994
ProQ; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities; Belongs to the ProQ family.
  
     0.466
Lgee_2279
IcmH (DotU).
  
    0.461
Lgee_1825
Hypothetical protein.
  
     0.458
yjeA
Endo-1,4-beta-xylanase.
  
 
   0.430
Your Current Organism:
Legionella geestiana
NCBI taxonomy Id: 45065
Other names: ATCC 49504, CCUG 44893, CIP 105569, DSM 21217, L. geestiana, NCTC 12373
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