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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lgee_2072Arginine-binding periplasmic protein. (253 aa)    
Predicted Functional Partners:
Lgee_0024
Sensory box histidine kinase/response regulator.
   
 
 0.548
Lgee_1507
Sensory box histidine kinase/response regulator.
   
 
 0.548
Lgee_0831
Sensory box histidine kinase/response regulator.
   
 
 0.508
Lgee_1733
Sensory box histidine kinase/response regulator.
   
 
 0.508
Lgee_0709
Regulatory protein (GGDEF and EAL domains).
     
 0.504
Lgee_0287
Hypothetical protein.
   
 
 0.474
gacS/letS
Transmission sensor LetS.
   
 
 0.474
Lgee_1714
29 kDa immunogenic protein.
 
  
 0.438
coxB
Cytochrome c oxidase subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
  
  
 0.414
Lgee_2071
Hypothetical protein.
       0.408
Your Current Organism:
Legionella geestiana
NCBI taxonomy Id: 45065
Other names: ATCC 49504, CCUG 44893, CIP 105569, DSM 21217, L. geestiana, NCTC 12373
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