STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Lgee_2153Serine protein kinase. (643 aa)    
Predicted Functional Partners:
Lgee_2152
Stress response UPF0229 protein YhbH; Belongs to the UPF0229 family.
 
  
 0.998
spo
SpoVR family protein.
 
  
 0.997
Lgee_1182
DNA binding stress protein; Belongs to the Dps family.
   
    0.823
wrbA
Flavoprotein WrbA (Trp repressor binding protein); Belongs to the WrbA family.
   
    0.774
Lgee_0626
Leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
    0.717
Lgee_1493
Osmotically inducible protein Y.
   
    0.644
phoH
Phosphate starvation inducible protein PhnH.
   
    0.539
pepN
Aminopeptidase.
       0.504
aroE
Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
       0.504
cca
tRNA nucleotidyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
     
 0.403
Your Current Organism:
Legionella geestiana
NCBI taxonomy Id: 45065
Other names: ATCC 49504, CCUG 44893, CIP 105569, DSM 21217, L. geestiana, NCTC 12373
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