Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Lgee_2239Putative phosphatidoglycerophosphate synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (200 aa)    
Predicted Functional Partners:
merA1
Mercuric reductase; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
 
     0.916
Lgee_0233
DNA-binding protein.
  
    0.790
cinA_1
Competence damage inducible protein CinA.
 
  
 0.537
Lgee_2241
YHS domain protein.
 
     0.532
Lgee_1732
Peptide synthetase, non-ribosomal.
  
  
 0.520
msrA
MsrA3 - peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
     
 0.508
Lgee_2242
Methionine sulfoxide reductase B.
       0.504
folD
Bifunctional protein FolD protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
  
  
 0.485
Lgee_2122
Acetyltransferase.
  
 
 0.470
psd
Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
    
 
 0.469
Your Current Organism:
Legionella geestiana
NCBI taxonomy Id: 45065
Other names: ATCC 49504, CCUG 44893, CIP 105569, DSM 21217, L. geestiana, NCTC 12373
Server load: low (40%) [HD]