Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
recX-2Recombination regulator RecX; Modulates RecA activity; Belongs to the RecX family. (152 aa)    
Predicted Functional Partners:
recA
Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 
 0.836
aacA-aphD
Aminoglycoside 6'-N-acetyltransferase.
 
     0.801
Lgra_0075
Homoserine kinase.
 
     0.747
Lgra_0110
Ankyrin repeats (3 copies).
  
     0.742
radA
DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
  
  
 0.736
Lgra_3017
Membrane protein.
  
     0.726
Lgra_3024
Hypothetical protein.
  
     0.722
Lgra_3019
TraU protein.
  
     0.721
Lgra_0134
Streptomycin 3''-adenylyltransferase; Multifunctional nucleotidyltransferase/glutamate rich protein GrpB/ribosomal protein alanine acetyltransferase.
  
     0.718
Lgra_3031
Bile acid beta-glucosidase.
  
     0.712
Your Current Organism:
Legionella gratiana
NCBI taxonomy Id: 45066
Other names: ATCC 49413, CCUG 44894, CIP 105267, DSM 21233, L. gratiana, NCTC 12388, strain Lyon 8420412
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