bioF protein (Legionella gratiana) - STRING interaction network

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Score

bioF

8-amino-7-oxononanoate synthase. (379 aa)

Predicted Functional Partners:

bioA

0.990

bioD

0.989

bioH

0.987

bioB

0.967

pksJ_1

0.876

bioC

0.874

pksJ_2

0.820

pksM

0.820

tdh

0.779

Lgra_2195

0.769

Your Current Organism:

Legionella gratiana

NCBI taxonomy Id: 45066
Other names: ATCC 49413, CCUG 44894, CIP 105267, DSM 21233, L. gratiana, NCTC 12388, strain Lyon 8420412

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Lgra_2195	bioA	Lgra_2195	Lgra_0345	acyl-CoA synthetase.	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.899
Lgra_2195	bioC	Lgra_2195	Lgra_0444	acyl-CoA synthetase.	Biotin synthase BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.	0.690
Lgra_2195	bioF	Lgra_2195	Lgra_0347	acyl-CoA synthetase.	8-amino-7-oxononanoate synthase.	0.769
Lgra_2195	bioH	Lgra_2195	Lgra_0348	acyl-CoA synthetase.	Biotin biosynthesis protein BioH.	0.856
Lgra_2195	pksJ_1	Lgra_2195	Lgra_1874	acyl-CoA synthetase.	Polyketide synthase, type I; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	0.999
Lgra_2195	pksJ_2	Lgra_2195	Lgra_1354	acyl-CoA synthetase.	Polyketide synthase module; Belongs to the ATP-dependent AMP-binding enzyme family.	0.999
Lgra_2195	pksM	Lgra_2195	Lgra_1928	acyl-CoA synthetase.	Polyketide synthase.	0.999
Lgra_2195	tdh	Lgra_2195	Lgra_2180	acyl-CoA synthetase.	Threonine(-3-)dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family.	0.649
bioA	Lgra_2195	Lgra_0345	Lgra_2195	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	acyl-CoA synthetase.	0.899
bioA	bioB	Lgra_0345	Lgra_0346	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.	0.995
bioA	bioC	Lgra_0345	Lgra_0444	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Biotin synthase BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.	0.675
bioA	bioD	Lgra_0345	Lgra_0349	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.	0.999
bioA	bioF	Lgra_0345	Lgra_0347	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	8-amino-7-oxononanoate synthase.	0.990
bioA	bioH	Lgra_0345	Lgra_0348	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Biotin biosynthesis protein BioH.	0.864
bioA	pksJ_1	Lgra_0345	Lgra_1874	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Polyketide synthase, type I; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	0.535
bioA	pksJ_2	Lgra_0345	Lgra_1354	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Polyketide synthase module; Belongs to the ATP-dependent AMP-binding enzyme family.	0.535
bioA	pksM	Lgra_0345	Lgra_1928	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Polyketide synthase.	0.535
bioB	bioA	Lgra_0346	Lgra_0345	Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.995
bioB	bioC	Lgra_0346	Lgra_0444	Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.	Biotin synthase BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.	0.970
bioB	bioD	Lgra_0346	Lgra_0349	Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.	Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.	0.999