STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Lgra_0453Glutamine amidotransferase. (248 aa)    
Predicted Functional Partners:
map_2
Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
  
    0.617
argS
Arginine tRNA synthetase.
   
  
 0.613
rplK
50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
   
    0.607
guaA
GMP synthetase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
    
 0.601
hpt
Pyrimidine phosphoribosyl transferase.
    
 0.599
Lgra_3137
3',5'-cyclic-nucleotide phosphodiesterase.
  
  
  0.598
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
 
 0.597
surE
Acid phosphatase SurE (Stationary phase survival protein); Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
 0.593
guaC
Guanosine monophosphate reductase GuaC.
  
 
 0.580
guaB
IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.580
Your Current Organism:
Legionella gratiana
NCBI taxonomy Id: 45066
Other names: ATCC 49413, CCUG 44894, CIP 105267, DSM 21233, L. gratiana, NCTC 12388, strain Lyon 8420412
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