Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rtxA2Structural toxin protein RtxA. (1352 aa)    
Predicted Functional Partners:
bepC
Agglutination protein.
 
    0.815
lssD_1
Secretion system protein D.
 
  
 0.799
apxIB_1
Toxin secretion ATP binding protein.
 
  
 0.773
ftsK
DNA translocase FtsK.
    
 
 0.736
Lgra_0956
Hypothetical protein.
 
     0.692
Lgra_0512
Periplasmic protein.
  
   
 0.683
rtxA-2
Structural toxin protein RtxA.
   
  0.565
bprV
Serine protease; Belongs to the peptidase S8 family.
  
 0.504
aprX
Subtilisin-like serine protease.
  
 0.504
ctpA_2
Carboxy-terminal protease; Belongs to the peptidase S41A family.
   
   0.446
Your Current Organism:
Legionella gratiana
NCBI taxonomy Id: 45066
Other names: ATCC 49413, CCUG 44894, CIP 105267, DSM 21233, L. gratiana, NCTC 12388, strain Lyon 8420412
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