| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| aceF | icd | Lgra_0322 | Lgra_3283 | Pyruvate dehydrogenase (dihydrolipoyltransacetylase component) E2p; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Isocitrate dehydrogenase. | 0.525 |
| aceF | lpdA | Lgra_0322 | Lgra_0323 | Pyruvate dehydrogenase (dihydrolipoyltransacetylase component) E2p; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Dihydrolipoyl dehydrogenase. | 0.998 |
| aceF | sdhA_2 | Lgra_0322 | Lgra_0642 | Pyruvate dehydrogenase (dihydrolipoyltransacetylase component) E2p; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Succinate dehydrogenase flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.509 |
| aceF | sdhB | Lgra_0322 | Lgra_0641 | Pyruvate dehydrogenase (dihydrolipoyltransacetylase component) E2p; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Succinate dehydrogenase iron-sulfur subunit. | 0.747 |
| aceF | sdhD | Lgra_0322 | Lgra_0643 | Pyruvate dehydrogenase (dihydrolipoyltransacetylase component) E2p; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Succinate dehydrogenase, hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH). | 0.408 |
| aceF | sucA | Lgra_0322 | Lgra_0640 | Pyruvate dehydrogenase (dihydrolipoyltransacetylase component) E2p; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 2-oxoglutarate dehydrogenase E1. | 0.983 |
| aceF | sucB | Lgra_0322 | Lgra_0639 | Pyruvate dehydrogenase (dihydrolipoyltransacetylase component) E2p; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Dihydrolipoamide succinyltransferase subunit E2; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.488 |
| aceF | sucD | Lgra_0322 | Lgra_0637 | Pyruvate dehydrogenase (dihydrolipoyltransacetylase component) E2p; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.955 |
| aceF | succ | Lgra_0322 | Lgra_0638 | Pyruvate dehydrogenase (dihydrolipoyltransacetylase component) E2p; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.966 |
| icd | aceF | Lgra_3283 | Lgra_0322 | Isocitrate dehydrogenase. | Pyruvate dehydrogenase (dihydrolipoyltransacetylase component) E2p; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.525 |
| icd | lpdA | Lgra_3283 | Lgra_0323 | Isocitrate dehydrogenase. | Dihydrolipoyl dehydrogenase. | 0.463 |
| icd | odp | Lgra_3283 | Lgra_2127 | Isocitrate dehydrogenase. | Branched-chain alpha-keto acid dehydrogenase subunit E2. | 0.525 |
| icd | sdhA_2 | Lgra_3283 | Lgra_0642 | Isocitrate dehydrogenase. | Succinate dehydrogenase flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.838 |
| icd | sdhB | Lgra_3283 | Lgra_0641 | Isocitrate dehydrogenase. | Succinate dehydrogenase iron-sulfur subunit. | 0.769 |
| icd | sdhD | Lgra_3283 | Lgra_0643 | Isocitrate dehydrogenase. | Succinate dehydrogenase, hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH). | 0.446 |
| icd | sucA | Lgra_3283 | Lgra_0640 | Isocitrate dehydrogenase. | 2-oxoglutarate dehydrogenase E1. | 0.971 |
| icd | sucB | Lgra_3283 | Lgra_0639 | Isocitrate dehydrogenase. | Dihydrolipoamide succinyltransferase subunit E2; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.525 |
| icd | sucD | Lgra_3283 | Lgra_0637 | Isocitrate dehydrogenase. | succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.783 |
| icd | succ | Lgra_3283 | Lgra_0638 | Isocitrate dehydrogenase. | succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.929 |
| lpdA | aceF | Lgra_0323 | Lgra_0322 | Dihydrolipoyl dehydrogenase. | Pyruvate dehydrogenase (dihydrolipoyltransacetylase component) E2p; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.998 |