Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ankDSubstrate of the Dot/Icm secretion system. (449 aa)    
Predicted Functional Partners:
dotA
Defect in organelle trafficking protein DotA.
       0.811
icmV
Intracellular multiplication protein IcmV.
       0.811
icmW
Intracellular multiplication protein IcmW.
       0.555
icmX
Intracellular multiplication protein IcmX.
       0.555
ptp
Serine carboxypeptidase.
    
  0.448
Lgra_1099
ATPase MoxR.
    
  0.442
rne
Ribonuclease E.
     
  0.419
trbG
Conjugal transfer protein trbG precursor.
    
   0.405
Your Current Organism:
Legionella gratiana
NCBI taxonomy Id: 45066
Other names: ATCC 49413, CCUG 44894, CIP 105267, DSM 21233, L. gratiana, NCTC 12388, strain Lyon 8420412
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